Jessica's Press Releases

Friday, August 16, 2019

QUANTUM GENOMICS Is Making Significant Advances in the Development of a New, Groundbreaking Drug to Help with Treatment-resistant Chronic Hypertension

Quantum Genomics are the creators of Firibastat, a first-in-class brain aminopeptidase inhibitor (BAPAI) that could potentially treat treatment-resistant hypertension by acting in the brain to interfere with the renin-angiotensin system.

It is estimated that there are around 150 million people worldwide that are affected by treatment-resistant hypertension, resulting in almost 10 million deaths per year from complications due to high blood pressure. With such a high number of people dealing with this chronic condition (around 1.1 billion people). For those with treatment resistant hypertension, they can be more susceptible to complications associated with hypertension such as heart failure, coronary artery disease, stroke, kidney disease and peripheral artery disease. Be alert to the latest news.

Standard treatments for hypertension include extensive lifestyle changes to address potential factors that may have contributed to the disease and multi-drug regimens, based on preference of the treating doctor.

Firibastat works by crossing the blood-brain barrier and modulating the brain renin-angiotensin system (RAS). RAS is a hormone system that controls blood pressure in part by modulating dilation and constriction of the blood vessels throughout the body, there is a RAS system in the brain, and at the peripheral level (kidney, heart…). By modulating the brain RAS, Firibastat decreases vasopressin release, decreases sympathetic nerve activity and improves baroreflex. These effects lead to a vasodilatation and an increased diuresis, thereby decreasing blood pressure.

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https://jessicapressreleases.blogspot.com/2018/05/rob-lowe-hosts-new-on-demand-segment-on.html

In the brain, Firibastat causes the inhibition of aminopeptidase A (APA) which is a key enzyme in the RAS. By inhibiting APA, Firibastat decreases levels of angiotensin III in the brain, a key protein that drives vasoconstriction. It is because of these actions that take place in the brain due to Firibastat that the drug could potentially address hypertension in the population of patients that have been resistant to current treatments of hypertension that act at the peripheral level.

Read this for more information.:

https://jessicapressreleases.blogspot.com/2018/05/autopets-opens-2018-out-of-box-thinking.html

Quantum Genomics has concluded NEW-HOPE, which is phase 2b trial in difficult-to-treat hypertension. The trial included 256 overweight and obese patients with primary hypertension across the US including 53% of minorities patients (of whom 38% of African-American), 44% are female, and 26% are above the age of 65 years old. This kind of population is more likely to suffer from resistant hypertension

Indeed treatment-resistant hypertension is not equally common across all demographics and ethnicities and was more prevalent in black, Hispanic, elderly and female populations. Obese patients with hypertension were 5 times more likely to be resistant to treatment.
Results of the trial indicated that treatment with Firibastat for 8 weeks resulted in significant (p<0.0001) decreased office systolic blood pressure by 9.5 mmHg (from 153.9 down to 144.4 mmHg) and was determined to be safe. Firibastat's efficiency was similar in black (-10.5mmHg) and non-black (-8.9mmHg) populations, contrary to other anti-hypertensive classes

The trial also showed a larger blood pressure decrease for patients with higher baseline hypertension, a predictive factor of resistant hypertension. Based on the outcome of the NEW-HOPE trial, Quantum Genomics will initiate a phase 3 pivotal trial in resistant hypertension with Firibastat.

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Based in Paris and New York, Quantum Genomics trades on the OTCQXt in the United States and Euronext Paris.

For more information, please visit http://www.quantum-genomics.com ,or follow us on Twitter and LinkedIn.

Media Contact:
NAME – Jean-Philippe MILON
EMAIL – jean-philippe.milon@quantum-genomics.com

All information are taken from the news source. We do not promise anything nor take any responsibility for anything the news owner claim. We just share the news as is. You can contact news owner directly in the message for more information.

Inspirus Ranked #2 Overall in the Baker's Dozen Client Satisfaction Ratings

Inspirus, a Sodexo Group company and leader in elevating employee experiences and optimizing organizational culture through people-focused solutions, has been recognized once again on the HRO Today Baker's Dozen list.

This latest achievement at the #2 spot marks a dozen consecutive years that Inspirus has been recognized on the HRO Baker's Dozen list. The HRO Today Baker's Dozen Customer Satisfaction Ratings are calculated solely on customer feedback. Through an online survey, verified respondents answered questions about the quality of service, deal size, and breadth of service received from their recognition provider. HRO Today aggregates this data using a predetermined algorithm, questions and categories are weighed based on importance, with special emphasis given to questions pertaining to the quality of customer service. These weights determine the final published rankings. Inspirus, where employees live the mission "Bring Joy to Work, One Experience at a Time™", has made the prestigious list for 12 consecutive years. More info here.

"Inspirus is committed to uniting employees around the world through innovation, engagement and authentic, memorable recognition. It is an honor to be ranked on this prestigious list for another year. We are so proud of our people, our service and our ability to meet the evolving needs of our clients," says CEO at Inspirus and Sodexo Benefits and Rewards Services, USA, Tatiana Frierson. Read all the related news.

Inspirus continues to drive the employee experience and the quality of life for employees around the globe. Its unique platform allows employees to connect, recognize and reward one another. Inspirus' clients benefit from our commitment to great service and digital innovation that provide the foundation, tools and methods to bring out the best in their teams and bring joy to work.

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https://jessicapressreleases.blogspot.com/2018/05/pet-perks-may-pay-off-for-employers-new.html

About Inspirus

Inspirus believes employees make up the foundation of culture, which is shaped and evolved through every day experiences that are essential to the development of strong, high-performing organizations. Through our technology and integrated solutions, we elevate the employee experience and enhance organizational culture by providing a holistic approach to the entire employee journey. We seek to influence the employee experience through our six Quality of Life dimensions: recognition, health and well-being, personal growth, physical environment, social interaction, and ease and efficiency.

Only Inspirus combines an integrated rewards engine, learning courses, communication tools, and analytics into a single platform spanning recognition, service anniversary, well-being, and diversity and inclusion. Inspirus aims to bring joy to work, one experience at a time.

Visit inspirus.com for more information.

A Handcrafted, One-of-a-Kind, Children's Airplane With Stadium Seating Donated to Ronald McDonald House Charities in New Hyde Park, NY

The employees of International Jet Interiors proudly designed, fabricated, and donated a custom handcrafted, one-of-a-kind children's aircraft to Ronald McDonald House Charities in New Hyde Park, Long Island, N.Y.

The airplane was designed to give children residents undergoing medical treatments and their family members a comfortable and fun way to watch outdoor movies at the RMHC facility. Equipped with stadium theater-style seating, lighting, RMHC custom colors and a built in projector, the RMHC themed airplane weighs over 1500 lbs. and was exclusively built for outdoor use.

At a Dedication Ceremony on Friday, August 2, 2019, International Jet Interiors employees and their families, along with staff and volunteers from the Ronald McDonald House Charities shared a special celebration at the New Hyde Park facility.

The Ronald McDonald House facility is a welcoming environment, where young children undergoing medical treatment at any of the neighboring Long Island hospitals, can stay with their families and feel the comforts of home – at no expense to the family. The New Hyde Park RMHC facility has the warmest, most welcoming staff and volunteers, as well as is an extraordinary "home", complete with private bedrooms, a bright and cheery living room, and beautiful dining spaces as well as a state of the art kitchen, gym, meditation room, outdoor relaxing spaces, outdoor playground and outdoor movies as well! Adjacent to a hospital, and easily accessible to local hospitals, the RMHC New Hyde Park facility is simply incredible. Be alert to the latest news.

The airplane construction began as a way for the International Jet Interiors team to share in a philanthropic project benefiting a special cause, and turned into a tremendous, 5 month labor of love for all involved. Each and every employee donated their time, passion and craftsmanship to create this one-of-a-kind children's airplane.

International Jet Interiors is a private jet modification and completion facility located in Ronkonkoma, NY at MacArthur Airport. Capabilities include design, engineering, fabrication, floor plan modifications, soundproofing, cabin management systems, lighting plans, upholstery, woodwork, metal plating, carpet design and installation, galley mods and cabin outfitting of private aircraft.

Sharing a passion for aviation and all the skills involved was a very meaningful way for the talented team at International Jet Interiors to help the young children and their families who are fortunate to be able to utilize a facility like the RMHC.

For inquiries, contact International Jet Interiors at 631.737.5900.

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4cats Sponsors the Cattery on the Mayhew Open Day 8th of September 2019 from 11.00 – 16.00

4cats Heimtierbedarf GmbH is delighted to be sponsoring the Mayhew Cattery for this year's Open Day Event.

Save the date and join the street party at Mayhew for a day of activities and a unique look behind the scenes at the work Mayhew does for animals and the community.

Visitors can visit the Cattery and meet the residents awaiting homes, tour the Veterinary Clinic and relax in the garden with veggie BBQ, live music and outdoor games. There will also be plenty of stalls to browse with treats for owners and their furry family members such as the 4cats catnip and valerian toys! Read this here.

The annual Open Day is a very important event for the charity as it encourages the community to get together for a fun family day out while raising much needed funds for the charities welfare efforts.

Tickets: Tickets will be available on the door priced at £3 for adults and £2 for children and concessions.

Location: Mayhew Animal Home, Trenmar Gardens, NW10 6BJ

Nearest Tube: Willesden Junction or Kensal Green (on street parking is available first come first serve however the streets do get very busy and we would recommend public transport)

About Mayhew:

Mayhew is an animal welfare charity working to improve the lives of dogs, cats and the people in the communities at home in London and internationally. They rescue hundreds of cats and dogs every year, provide veterinary care to thousands, and deliver community projects that improve the lives of both animals and people across the globe. Read here.

About 4cats Heimtierbedarf GmbH:

4cats are a family run business that specialises in high-quality valerian and catnip toys. For the catnip toys they use a special formula of catnip that is their own creation and is called 4catsnip. Through long testing and trialling they found that this particular mixture works especially well even for cats that usually don't react to catnip at all! While they won't disclose their special recipe they can certainly confirm that it is 100% organic and of high quality.

All of their cat toys are 100% designed, made and packed in Germany in their premises in Stolberg by Aachen. They only use high-quality ingredients and material and all toys undergo the highest quality assurance to ensure that customers are satisfied and their cats will have long lasting fun and entertainment with them.

The DVI Group Named on Inc. Magazine’s Annual List of America’s Fastest-Growing Private Companies—the Inc. 5000

The Inc. 5000 list represents a unique look at the most successful companies within the American economy's most dynamic segment—its independent small businesses. Thanks to a three-year revenue growth of 244% percent, The DVI Group joins Microsoft, Dell, Domino's Pizza, Pandora, Timberland, LinkedIn, Yelp, Zillow, and many other well-known names that gained their first national exposure as honorees on the Inc. 5000.

"We're excited about how The DVI Group is performing as we enter into our 20th year," says DVI CEO Matthew Lopes. "Our clients have entrusted us with providing innovative video content and integrated marketing services for their world-renowned brands, and the success of our creative partnerships is evident in the recognition and awards that have happened as a result. From being short-listed at Cannes, to being ranked in the Inc. 5000. I'm extremely proud of our client relationships and the hard work and dedication of everyone at DVI who have made achieving this honor possible." Read all the latest news.

Not only have the companies on the 2019 Inc. 5000 been very competitive within their markets, but the list as a whole shows staggering growth compared with prior lists. The 2019 Inc. 5000 achieved an astounding three-year average growth of 454 percent, and a median rate of 157 percent. The Inc. 5000's aggregate revenue was $237.7 billion in 2018, accounting for 1,216,308 jobs over the past three years.

Complete results of the Inc. 5000, including an interactive database that can be sorted by industry, region, and other criteria, can be found at http://www.inc.com/inc5000 or http://www.inc.com/profile/the-dvi-group to go straight to The DVI Group profile.

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https://jessicapressreleases.blogspot.com/2018/05/fareportals-cheapoaircom-wins-gold.html

"The companies on this year's Inc. 5000 have followed so many different paths to success," says Inc. editor in chief James Ledbetter. "There's no single course you can follow or investment you can take that will guarantee this kind of spectacular growth. But what they have in common is persistence and seizing opportunities."

CEO, Matthew Lopes and key members of the DVI Group team, will toast to DVI's impressive first-time appearance on the inc.5000 list by joining innovators and business leaders at The annual Inc. 5000 event honoring the companies on the list which will be held October 10 to 12, 2019, at the JW Marriott Desert Ridge Resort and Spa in Phoenix, Arizona.

Be alert to read related news.:

https://jessicapressreleases.blogspot.com/2018/05/shmoop-prepares-students-for-ap-season.html

ABOUT THE DVI GROUP
Founded in 2000, The DVI Group is a strategic video communications agency based in Atlanta, Georgia. Working from the ideology that the future of communications starts with video, The DVI Group's video solutions touch every aspect of the client's business ranging from human resources and learning to marketing and communications. DVI has produced award-winning video content, and digital marketing campaigns, for world-renowned brands like Delta Air Lines, Doosan Infracore North America, Hansgrohe, MBUSA, The Home Depot, and InterContinental Hotels Group. Read here.

More about Inc. and the Inc. 5000

Methodology
The 2019 Inc. 5000 is ranked according to percentage revenue growth when comparing 2015 and 2018. To qualify, companies must have been founded and generating revenue by March 31, 2015. They had to be U.S.-based, privately held, for profit, and independent—not subsidiaries or divisions of other companies—as of December 31, 2018. (Since then, a number of companies on the list have gone public or been acquired.) The minimum revenue required for 2015 is $100,000; the minimum for 2018 is $2 million. As always, Inc. reserves the right to decline applicants for subjective reasons.

About Inc. Media
Founded in 1979 and acquired in 2005 by Mansueto Ventures, Inc. is the only major brand dedicated exclusively to owners and managers of growing private companies, with the aim to deliver real solutions for today's innovative company builders. Inc. took home the National Magazine Award for General Excellence in both 2014 and 2012. The total monthly audience reach for the brand has been growing significantly, from 2,000,000 in 2010 to more than 20,000,000 today. For more information, visit http://www.inc.com.
The Inc. 5000 is a list of the fastest-growing private companies in the nation. Started in 1982, this prestigious list has become the hallmark of entrepreneurial success.

Women In Trucking Association President and CEO Ellen Voie Named Cinderella to CEO of the Year

Women In Trucking Association (WIT) President and CEO Ellen Voie was named the 2019 Cinderella to CEO of the Year, along with winning her award category, "Climbing the Beanstalk" for cultivating an innovative improvement to the workplace to create inroads for women to achieve career goals and enhanced work-life balance opportunities for all genders.

The Cinderella to CEO Awards recognize women who have overcome obstacles to change businesses, communities and industries for the better. The inaugural awards, inspired by the book From Cinderella to CEO, How to Master the 10 Lessons of Fairy Tales to Transform Your Work Life by Cary Broussard, occurred Thursday, August 8 at the JW Marriott Essex House, honoring 200 women across industries and communities who were nominated for the awards.

"Our goal is to accelerate the successes of women who have worked hard and helped others to also succeed by connecting them to opportunities and each other," said Cary Broussard, CEO of Broussard Global. "In 2030, women in the U.S. are expected to control 75 percent of the wealth in this country. We want the wealth to be in the good, caring hands of those who strive to make the world a better place."

Nine category winners, including Voie, were recognized by a distinguished Cinderella to CEO panel of judges for their support of other women, their transformational ability to overcome obstacles and barriers, and their desire to motivate others to accomplish their dreams. Each award category is tied to a chapter in Broussard's book.

"I am so honored to receive the very first Cinderella to CEO award, as there were hundreds of nominations featuring some amazing women who have done truly notable and altruistic projects," said Voie. "I am especially thrilled to be recognized by an organization outside the trucking industry, which makes the award even more special." Read related news here.

Prizes were provided by Carnival Cruise Line, 2020 Women on Boards, KPMG PGA golf clinics, The George Washington University Center for Excellence in Public Leadership, Broussard Global and the Cinderella to CEO "WAND" ambassadors.

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About Women In Trucking Association, Inc.
Women In Trucking Association, Inc. is a nonprofit association established to encourage the employment of women in the trucking industry, promote their accomplishments and minimize obstacles faced by women working in the trucking industry. Membership is not limited to women, as 17 percent of its members are men who support the mission. Women In Trucking is supported by its members and the generosity of Gold Level Partners: Arrow Truck Sales, Bendix Commercial Vehicle Systems, BMO Transportation Finance, Daimler Trucks North America, Expediter Services, FedEx Freight, Great Dane, J.B. Hunt Transport, Michelin North America, Peterbilt Motors Company, Ryder System, Inc., and Walmart. Follow WIT on Twitter, Facebook, or LinkedIn. For more information, visit http://www.womenintrucking.org or call 888-464-9482.

Keynotes Announced for 2019 Global SAFe® Summit Being Held September 29 – October 4 in San Diego, California

Scaled Agile, Inc., provider of the world's leading framework for enterprise agility, today announced four keynote speakers for the upcoming 2019 Global SAFe Summit, which will take place September 29 – October 4 in San Diego, California. With over 2,000 attendees expected, the fourth annual Global SAFe Summit will be the largest-ever gathering focused exclusively on the Scaled Agile Framework® (SAFe®) and its community of practice.

This year's event will feature keynotes from thought leaders in Lean-Agile practices, product-based development, collaboration frameworks, and personal transformation.

—Recognized as one of the world's foremost authorities on Lean-Agile best practices, SAFe creator and chief methodologist, Dean Leffingwell will present "Competing in the Age of Software with Business Agility." Leffingwell will share the latest thinking in scalable, Lean-Agile technical practices, as well as guidance on how to extend the Agile mindset and practices to all aspects of the business.

—Dr. Mik Kersten, founder of Tasktop and best-selling author of Project to Product, will present "Project to Product: From Flow Metrics to SAFe." The Value Stream Network pioneer shows how a product operating model can provide the critical glue between the hierarchical and finance-oriented structures of the business and the agility enabled by delivery teams adopting SAFe. "Mik Kersten has laid new groundwork in the area of product-based development," said Leffingwell. "So we're delighted that he'll be addressing the Summit audience at a time when they are making critical decisions on how to transform into product-centric innovators that can compete and thrive in the age of software."

—Known as classical music's "No.1 Maverick," Jade Simmons is a concert pianist and author of the best-selling book, Audacious Prayers for World Changers. In her presentation, "How to Move Like a Maverick," Simmons will discuss cultivating innovation and originality, the strategies behind audacious leadership, and the tools to unleash momentum in life and business.

—Author, inventor, and expert on Agile software development, Luke Hohmann will present "Tackling Awesome Super Problems." Hohmann will demonstrate how decision-making and collaboration approaches pioneered by the Agile community can be used to tackle the most extreme challenges of software development.

Last year's event sold out, so prospective attendees are encouraged to register now and secure a spot for the 2019 Global SAFe Summit.

About Scaled Agile, Inc.:
Scaled Agile, Inc. is the provider of SAFe®, the world's leading framework for enterprise agility. Through learning and certification, a global partner network, and a growing community of over 450,000 trained professionals, Scaled Agile helps enterprises build better systems, increase employee engagement, and improve business outcomes. Scaled Agile is a contributing member of the Pledge 1% corporate philanthropy and community service movement. Learn about Scaled Agile and SAFe at scaledagile.com.

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