Thursday, October 4, 2018

In Vitro Maturation: Maturing Immature Eggs Outside of the Ovaries Offers A Successful Fertility Option for Many

Increasing success with the way eggs are matured outside a person's ovaries has given new hope to women who have difficulty becoming pregnant, especially those with diseases or disorders that make use of conventional in vitro fertilization techniques less effective – or even risky.

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So, states Ralf Zimmermann MD, reproductive endocrinologist and infertility specialist and medical director of Neway Fertility in New York City, who says the improved fertility process -- in vitro maturation (IVM) – is becoming the technique of choice for promoting pregnancy in patients with conditions like polycystic ovarian syndrome, a common hormonal disorder, or in women with cancer or with limited eggs, often due to advanced age.

"Research also has demonstrated IVM's success in preserving healthy oocytes – immature ovum or egg cells – harvested from women facing cancer treatments that are likely to make them infertile," explains Dr. Zimmermann,

He cites comments made in 2017 by authors of a report in the journal, Reproductive Medicine and Biology, that improved cancer survival rates are increasing demand for fertility preservation. An estimated 20 percent of gynecologic cancers occur in women of reproductive age. Survivors of these cancers often undergo radiation and chemotherapy regimens that affect ovarian function.

Unlike in vitro fertilization in which a woman is directly given medications to stimulate egg production and maturation inside her ovaries, IVM involves harvesting immature eggs without stimulating the ovaries – or only minimally stimulating them – and then maturing the eggs in a laboratory using a protein-rich culture medium and small amounts of hormones, Dr. Zimmermann explains.

Once matured, the eggs are fertilized through intracytoplasmic sperm injection, in which one sperm is injected into each egg with a small needle. The resulting embryos can then be transferred immediately to the uterus or preserved through a freezing technique called vitrification, or "flash freezing", and introduced to the uterus later when a woman is ready to become pregnant.

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"IVM is an important fertility alternative for women with polycystic ovarian syndrome because these patients are prone to developing ovarian hyperstimulation syndrome (OHSS) when exposed to the drugs used in traditional in vitro fertilization," says Dr. Zimmermann. OHSS occurs when fluid from the ovary shifts to other parts of the body, including abdomen and lungs. It is a common complication of fertility treatment and can develop into a serious – even fatal – disorder.

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For women recovering from cancer, conventional in vitro fertilization drugs used to stimulate the ovaries may contain hormonal components that also stimulate any remaining cancer tissue in the body. "That's why IVM can be a more acceptable fertility approach for these patients," Dr. Zimmermann says.

Others who may benefit from IVM include women with limited remaining eggs and those who have blocked or removed fallopian tubes or suffer from ovulation problems or autoimmune diseases.

Besides the enhanced safety that IVM affords women with various disorders, the technique is oftentimes more convenient than in vitro fertilization and can be performed at lower cost.

Dr. Zimmermann concurs with researchers who say IVM still has "a long way to go," but says the technique continues to advance at an amazing rate. In fact, authors of a study published in August 2018 in the Journal of Ovarian Research report that, in women of reproductive age who have polycystic ovarian syndrome, IVM is proving to be a "convenient option" with a live birth rate like that of standard in vitro fertilization.

"Ongoing advancements in IVM techniques are leading to more successful outcomes," Dr. Zimmermann says. "As we learn more in our clinical practice, we will be better able to select patients who can achieve the highest results from IVM."

Bio: Dr. Ralf Zimmermann is dual board-certified in OB/GYN and Reproductive Endocrinology/Infertility. As Neway Fertility's Medical Director and fertility specialist, Dr. Ralf Zimmermann comes from an accomplished background in reproductive endocrinology and assisted reproductive technologies (ART), with a special interest in the psychological factors of infertility treatment. http://www.newayfertility.com

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WaterField Delivers Professional Style with New Vero Leather Sleeve for Microsoft Surface Pro 6 and Surface Laptop 2

WaterField Designs, an innovative leader in custom-fitted laptop sleeves and designer bags and cases for consumer electronics, announces the sumptuous, full-grain, distressed Vero Leather Sleeve for the new Microsoft Surface Pro 6 and Surface Laptop 2. Handcrafted from the strongest part of the hide, the leather laptop sleeve is built to last and develops a beautiful patina over time. An ultra-plush liner cushions the Surface Pro 6 or Surface Laptop 2 inside. Slim and elegant, the Vero Leather Sleeve ups the style quotient for any professional.

"The first step to protecting your laptop is to have a perfectly-sized laptop case to cushion it while in transit," explained company founder, Gary Waterfield. "The custom-fitted, Vero Leather Sleeve cradles the Surface with an interior that is so soft, you'll probably wish you could crawl in there yourself to take a nap. The leather ages well and gets better and better looking the more you use it."

The new Vero Leather Sleeve secures and protects the Microsoft Surface Pro 6 or Surface Laptop 2 without zippers. A snug fit keeps the laptop inside while a leather strip on the sleeve's base serves as a hand grip to assist with quick removal. Inside the luxurious leather sleeve, an exceptionally plush liner absorbs shock as it safeguards the laptop. A customized rear, leather slot holds the Surface Pen while in transit. Travelers passing through airport security can leave the laptop protected while it makes its way through the x-ray apparatus, thereby maximizing efficiency while minimizing potential damage.

Features at-a-glance:

The Vero Leather Sleeve is available in grizzly or chocolate premium, distressed, full-grain leather. The new leather laptop sleeve is available in custom sizes for the Microsoft Surface Pro 6 and Microsoft Laptop 2, as well as the 13-inch MacBook Pro with TouchBar and the 15-inch MacBook Pro with TouchBar. Additional WaterField Designs bags and sleeves for the Microsoft Surface Pro 6 include the SleeveCase, the Dash Sleeve and the Outback Solo. To protect and store Surface accessories, WaterField offers the Surface Accessories Pouch. Click here to read the latest news.

Availability & Pricing
Price: $119 — Surface Pro 6, Surface Laptop 2, 13-inch MacBook Pro with TouchBar. $129 — 15-inch MacBook Pro with TouchBar.
Colors: Grizzly brown or chocolate distressed, full-grain leather.
Available for pre-order from the WaterField Designs online store.
Shipping begins October 19 for MacBook sizes; November 2 for Surface sizes.

Other compatible sleeves: SleeveCase ($69), Dash Sleeve ($89), Outback Solo ($159). Also see the Surface Accessories Pouch ($79). All products are available exclusively from the WaterField Designs online store.

About WaterField Designs
WaterField Designs is an innovative San Francisco designer and manufacturer of bags and cases for tech-savvy consumers who want to stylishly and responsibly transport their technology. WaterField manufactures custom-fitted, high-quality cases and bags for a full-range of laptop computers, smartphones, tablets, gaming devices and other digital gear. All products are manufactured to exacting standards entirely in San Francisco. More information available at "Our Story".

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Angela Josephine Premieres Dazzling "Go Easy" Music Video on Popdust

Watch "Go Easy" on Popdust

Though she's long been associated with Traverse City, MI, Angela Josephine has a deep connection to Ireland. Motifs and melodies from the Celtic Isles are woven through her entire body of work. Sometimes these are subtle, and sometimes they're as bold as an Ulster landscape. They were there on A Restful Sense of Urgency, the landmark album that established her as one of the brightest voices of the resurgent Northern Michigan arts scene. They were audible on the 2006 set Grace Exhaled, and they were unmistakably present on Stone Bright Solid, Volume 1, a 2012 collaboration with the Ypsilanti, MI producer and songwriter Chris Bathgate. "I've been inspired by the Northern Michigan landscape," she says, "but just recently found out through ancestry that I may have connections to Northern Ireland. It makes the pull to that region even more discernible and my connection more profound."

Now comes Daylight (Stone Bright Solid, Volume 2), which has already garnered praise from Guitar Girl, Cross Rhythms, Innocent Words, and many other independent music publications. For the set, she's shot two gorgeous videos that showcase her embrace of the folk traditions of the British Isles. Helen Rollins, the Belfast-based director of "Go Easy", filmed the clip in Northern Ireland, and has made brilliant use of settings she knows well. And Josephine, who worked with the award-winning Irish choreographer Maureen Butler to create the videos, looks right at home. Read this for more information.

The new tracks continue Angela Josephine's artistic relationship with Bathgate, who returns to the producer's chair for Daylight. This time, he moves from behind the board to behind the mic: "Go Easy" is a duet between the sweet-voiced Bathgate and Josephine. The song showcases the star's remarkable versatility, her formidable instrumental skill, and her well-chronicled mastery of mood.

The video for the intimate "Go Easy" explores the breathtaking interior of Riddel's Warehouse, a historic building in Belfast associated with the cast iron trade. The Irish actor Phil Dixon takes the part sung on the recording by Chris Bathgate, and joins Josephine in a stately but emotionally suggestive dance on the floor of the old industrial building.

Watch "Go Easy" on Popdust

Follow Angela Josephine Website | Facebook | Twitter | Instagram

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Strengthening Our Schools: Cancer Support Community CNJ Providing Support for Children in the Classroom Impacted by Cancer

Among the myriad issues facing children in schools across the country is the emotional, social and academic toll of cancer in the family. It is easy to understand and support a child who is diagnosed with cancer, but much harder to imagine the impact for a child whose parent, grandparent, or other loved one is facing the disease. Many times, schools are unaware the family is dealing with this significant health issue; it comes to the forefront after a student's grades drop, he or she misses classes, or, in extreme cases, acts out in the classroom. Be alert to the latest news.

Cancer Support Community Central New Jersey (CSCCNJ), located in Bedminster, NJ, understands the importance of providing support for these vulnerable students, as well as the school and childcare personnel with whom they spend the majority of their day. Many times, caregivers, teachers, guidance counselors and other school professionals will become "first responders" in this crisis when students approach them with news of a cancer diagnosis in the family.

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It is important for school and childcare professionals to feel empowered with tools and knowledge, so, since 2008, CSCCNJ has offered Strengthening Our Schools (SOS) to provide the necessary tools and information to benefit these educators. This annual event, offered at no charge to any professional who interacts with children on a regular basis, is scheduled for October 19, 2018 at the Bridgewater Manor in Bridgewater, NJ. It is a day-long, regional conference that offers tools and information to assist school and childcare personnel in their work with families affected by cancer. Each participant will attend two lectures, offered by nationally-renowned medical oncologists, and a series of smaller workshops led by oncology social work and allied health professionals.

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Strengthening Our Schools is the centerpiece of CSCCNJ's year-round efforts to address the significant unmet needs for adolescents and teens facing a cancer diagnosis or the diagnosis/death of a family member. Every week, there are almost 33,000 new cases of cancer, according to the American Cancer Society, and over 1,670 people will die every day, so the problem is unrelenting. In response, CSCCNJ offers school-based support groups during lunches or free periods. Since 2015, in response to the needs identified by school and community personnel at Strengthening Our Schools, CSCCNJ has started groups in five local high schools with plans to move into additional high schools and the first middle school in 2019.

The impact of school-based support groups is evident to the professionals who have seen the positive change in students. Coleen Butler, Director of Guidance, K-12 in the Somerset Hills School District, has seen the effect on her students at Bernards High School. "Our Teens Connect group resembles the characters from The Breakfast Club in that the members are all completely different, but they are connected by a circumstance that is very difficult—Cancer," Butler says, "I have watched The Athlete and The Brain, who might have never spoken to each other before, bond in a way that they support one another both in and out of group."

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Katherine Schaible, LSW, and Program Coordinator at CSCCNJ, facilitates some of these school-based support groups. Schaible notes, "It's important for these teens to know that they are not alone. The group helps to reduce feelings of isolation and provide a model for healthy coping skills that will carry these students throughout their lives." By addressing this life changing crisis at a critical state in their development, CSCCNJ can positively impact young people affected by cancer and teach them important coping skills that will last throughout their lifetime.

School-based support groups are open to both students whose loved ones are living with a cancer diagnosis and those who are bereaved. It is a place to connect with others who understand what they are experiencing. One student says, "Having a safe place to open up and where people can relate and give advice was so helpful."

Butler concludes, "As we have seen in The Breakfast Club, being a teenager is hard; but being a teenager whose life has been affected by cancer is even harder."

For more information about Strengthening Our Schools, visit us online at http://www.cancersupportcnj.org/sos or call Jill Kaplan, Program Director, at 908-658-5400 x3.

About Cancer Support Community Central New Jersey: Cancer Support Community of Central New Jersey (CSCCNJ) is a registered 501c(3) and an independently licensed affiliate of Cancer Support Community, an international non-profit organization. As experts in oncology mental health, the organization provides support, education, and hope to all people with cancer and their loved ones, so that no one faces cancer alone®. Backed by evidence that the best cancer care includes social and emotional support, CSCCNJ creates a supportive community to help individuals live with, through and beyond cancer. At no cost to patients, family members and caregivers, the organization delivers essential programs and services including individual and group support, educational workshops, nutrition and healthy cooking education, classes to enhance health and wellness and social activities for the entire family. For more information please visit their website at cancersupportcnj.org or call (908) 658-5400.

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DSCC Releases Annual Foldable Display Technology and Market Report

Display Supply Chain Consultants (DSCC) has released the industry's first report dedicated to foldable display technology and the foldable display market. This report took 9 months to produce, provides deep insight into what it will take to commercialize foldable displays and forecasts foldable display yields, costs, capacity, shipments, prices, revenues, area and more.

The report reveals:

The report also answers the following important questions:

DSCC projects the foldable display market will start out slow reaching 3.1M units in 2019 with Samsung Electronics and Huawei launching foldable smartphones in Q1'19. After 2019, growth will accelerate as shown in Figures 1 and 2 as costs and prices fall, availability improves, and competition increases enabling foldable displays to expand into tablets, notebook PCs and other market segments. By 2022, DSCC sees the foldable market for all applications at 63M units, a 173% CAGR. On a revenue basis, DSCC shows 151% CAGR in display revenues to $8.9B in 2022.

According to DSCC CEO Ross Young, "This was a very challenging report to write as it encompasses so many different aspects of the display market. It required expertise on display manufacturing, process flows, many different types of display materials and how they are manufactured, hinge solutions, cost modeling, capacity modeling, brand and panel supplier surveys and roadmap discussions, demand forecasting, price forecasting and calculating supply vs. demand. We also met with many brands and panel suppliers and discussed their roadmaps and most are quite excited about the long-term prospects for foldable displays. They are hoping the innovative form factor and ability to incorporate larger displays into smaller form factors will drive ASPs and revenues higher."

For more information on DSCC's 250-slide Foldable Display Market and Technology Report including a detailed table of contents, please visit https://www.displaysupplychain.com/foldable-display.html.

DSCC is also hosting the Future of Display Technologies and Markets Conference on November 6th at the Santa Clara Convention Center in Santa Clara, CA. where it will be discussing its outlook for foldable displays. More information for this event can be found at: https://bit.ly/2R2UY5z.

DSCC CEO Ross Young will also be presenting excerpts of this and other reports at the Bay Area SID Chapter meeting on October 16th. Please visit http://www.sid.org/Chapters/Americas/BAChapter.aspx for more information.

About DSCC
Display Supply Chain Consultants (DSCC) was formed by experienced display market analysts from throughout the display supply chain and delivers valuable insights through consulting, syndicated reports and events. The company has offices in the US, China, Japan and Korea. DSCC can be found on the web at http://www.displaysupplychain.com and can be reached in the US at info@displaysupplychain.com or (512) 577-3672.

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Attorney Sharon Handy Recognized for Outstanding Community Involvement

The Girl Scouts of Kentuckiana recently bestowed the Tough Cookie award upon attorney Sharon Handy, of Seiller Waterman LLC. The Tough Cookie award is presented to outstanding women who embody courage, confidence, and character while supporting Girl Scouting, young women, and the community.

"Sharon is a woman whose life exemplifies the value of community service intrinsic to Girl Scouts," said Robert Waterman, a founder of Seiller Waterman LLC.

Handy also recently participated in Le Tour de Pork bike ride with Tammy Naples, a paralegal in the firm, Tammy's sister Tracey Hazelwood, and another friend. The ride is a benefit for the Ohio River Greenway, which is nearing completion. The multi-use trail will ultimately run for 7.5 miles along the banks of the Ohio River from Jeffersonville, through Clarksville, to New Albany, Indiana. Be alert to read related news.

Taking her community involvement even further, Handy was also recently elected to the board of directors of the Community Foundation of Southern Indiana. The organization offers a range of charitable funds, allowing individuals, families, businesses, and not-for-profits to choose the best vehicle(s) to help accomplish their philanthropic goals.

The Community Foundation of Southern Indiana administers over $116 million in assets, annually granting more than $4.5 million to causes that impact the community, stewarding more than 240 individual funds, and providing leadership on important community issues in Southern Indiana.

About Sharon Handy, Seiller Waterman LLC
Sharon Handy focuses on Commercial Transactions, Business Law, Charitable Organizations, Probate & Estate Administration, Estate & Tax Planning, Trusts, Real Estate, Employment Law, Employee Benefits (ERISA), Elder Law and Tax. For more information, please call (502) 371-3501, or visit http://www.derbycitylaw.com.

About the NALA™
The NALA offers small and medium-sized businesses effective ways to reach customers through new media. As a single-agency source, the NALA helps businesses flourish in their local community. The NALA's mission is to promote a business' relevant and newsworthy events and achievements, both online and through traditional media. The information and content in this article are not in conjunction with the views of the NALA. For media inquiries, please call 805.650.6121, ext. 361.

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Aladtec Team Will Demo Software at Minnesota Fire Chiefs Conference

Health, wellness, and education are themes Minnesota Fire Chiefs Association members will hear championed when they gather Oct. 10-13 for their annual conference and expo at the RiverCentre.

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Along with education and fellowship, department leaders will shop products and services offered by dozens of vendors -- including Aladtec, the premier provider of scheduling software and workforce management solutions for public safety.

Conference attendees are invited to stop by the Aladtec display during the trade show, from noon to 7 p.m., Thursday, Oct. 11, and from 8 a.m. to 1:30 p.m., Friday, Oct. 12. Senior Account Representative Brad Parmeter and Support Specialist Nancy Newton will provide demonstrations of the software and answer any questions. Read this here.

The Aladtec system easily handles the complex scheduling and unique rotation requirements common in fire service. Its features allow members to submit availability, request time off and initiate shift trades -- all from a smartphone, tablet or desktop. It helps leaders monitor and meet minimum staffing requirements, helps control overtime, integrates with payroll, and allows agencies to track certifications and licensing. Aladtec e-forms speed up rig checks and provide airtight documentation.

Firefighter-paramedic Jerry Craddock recalls the hassles of trying to check a schedule, request time off or swap a shift before Mentor (OH) Fire & Rescue subscribed to Aladtec. He'd either need to drive to the station or phone in to check a paper schedule posted somewhere. Be alert to the latest news.

"It was crazy, but when we got Aladtec, it all became so organized," said Craddock. "There was quick acceptance. It streamlined what was once a chore. I believe that if they took Aladtec's Fire Manager away from us, there would be a mutiny." Read all the latest news.

Watch this short video to see how the Maplewood (MN) Fire Dept. uses Aladtec to schedule multiple crews at several stations. Read news here.

Other program highlights for attendees include discussions on legislative issues, advice on gaining community support for construction of a new fire station, cancer prevalence and prevention as it relates to fire service, PTSD and firefighter mental health, and how department leaders can engage and keep non-career firefighters motivated to serve their communities for many years.

Aladtec is proud to have 26 fire departments in the greater Twin Cities area as customers, and hundreds more across the U.S. across the U.S and Canada.

For a free demonstration, visit http://www.aladtec.com. Call 888-749-5550 with questions, or to arrange a customized demonstration for your agency.

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CONTACT INFORMATION:

Aladtec, Inc.
387 Arrow Court
River Falls, WI 54022
(888) 749-5550
(801) 406-5550 Fax
steve(at)aladtec.com
info(at)aladtec.com

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